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Human MFGE8 ELISA Kit (Lactadherin) (ab213810)

Key features and details

  • Sensitivity: 10 pg/ml
  • Range: 62.5 pg/ml - 4000 pg/ml
  • Sample type: Cell culture supernatant, EDTA Plasma, Hep Plasma, Milk, Saliva, Serum, Urine
  • Detection method: Colorimetric
  • Assay type: Sandwich (quantitative)
  • Reacts with: Human

Properties

  • Storage instructions

    Store at -20°C. Please refer to protocols.
  • Components Identifier 1 x 96 tests
    ABC Diluent Buffer Blue Cap 1 x 12ml
    Adhesive Plate Seal 4 units
    Antibody Diluent Buffer Green Cap 1 x 12ml
    Anti-Human MFGE8 coated Microplate (12 x 8 wells) 1 unit
    Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl
    Biotinylated anti-Human MFGE8 antibody 1 x 130µl
    Lyophilized recombinant Human MFGE8 standard 2 vials
    Sample Diluent Buffer Green Cap 1 x 30ml
    TMB Color Developing Agent Black Cap 1 x 10ml
    TMB Stop Solution Yellow Cap 1 x 10ml

  • Research areas

  • Function

    Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
    Medin is the main constituent of aortic medial amyloid.

  • Tissue specificity

    Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.

  • Sequence similarities

    Contains 1 EGF-like domain.
    Contains 2 F5/8 type C domains.

  • Post-translational
    modifications

    Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.

  • Cellular localization

    Membrane. Secreted.
  • Information by UniProt

  • Alternative names

    • BA46
    • Breast epithelial antigen BA46
    • EDIL1
    • HMFG
    • hP47
    • HsT19888
    • Lactadherin
    • Medin
    • MFG-E8
    • MFGE8
    • MFGM
    • MFGM_HUMAN
    • Milk fat globule EGF factor 8
    • Milk fat globule EGF factor 8 protein
    • Milk fat globule-EGF factor 8
    • O acetyl disialoganglioside synthase
    • OAcGD3S
    • SED1
    • SPAG10
    • Sperm associated antigen 10
    • Sperm surface protein hP47
    see all

  • Database links

    Images

    • Human MFGE8 ELISA Kit (Lactadherin) (ab213810) Standard Curve
      Human MFGE8 ELISA Kit (Lactadherin) (ab213810) Standard Curve

      Human MFGE8 ELISA Kit (Lactadherin) (ab213810) Standard Curve

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