Human IL-18 R beta ELISA Kit (ab113325)
Key features and details
- Sensitivity: 12 pg/ml
- Range: 12.3 pg/ml - 3000 pg/ml
- Sample type: Cell culture supernatant, Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 500X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml 5X Assay Diluent D 1 x 15ml Biotinylated anti-Human IL-18 R beta 2 vials IL-18 R beta Microplate 1 unit Recombinant Human IL-18 R beta Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Function
Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. -
Tissue specificity
Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. -
Sequence similarities
Belongs to the interleukin-1 receptor family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
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Alternative names
- IL18RAP
- Accessory protein like
- Accessory protein-like
see all -
Database links
- Entrez Gene: 8807 Human
- Omim: 604509 Human
- SwissProt: O95256 Human
- Unigene: 158315 Human
Images
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Representative Standard Curve
Representative Standard Curve using ab113325
