Human Glycogen Synthase 1 Antibody Pair - BSA and Azide free (ab241835)
Key features and details
- Unconjugated capture and detector antibodies
- Adaptable to any antibody pair-based assay format
- Antibody concentration ~ 1 mg/ml
- BSA and azide free buffer - ready for conjugation
- Reacts with: Human
Overview
-
Product name
Human Glycogen Synthase 1 Antibody Pair - BSA and Azide free
See all Glycogen synthase 1/GYS1 kits -
Assay type
ELISA set -
Range
62.5 pg/ml - 4000 pg/ml -
Species reactivity
Reacts with: Human -
Product overview
The Antibody Pair can be used to quantify Human Glycogen Synthase 1. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.
For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab214031), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.
Download SDS here.
-
Tested applications
Suitable for: Sandwich ELISAmore details -
Platform
Reagents
Properties
-
Storage instructions
Store at +4°C. Please refer to protocols. -
Carrier free
Yes -
Components 10 x 96 tests Human Glycogen Synthase 1 Capture Antibody (unconjugated) 1 x 100µg Human Glycogen Synthase 1 Detector Antibody (unconjugated) 1 x 100µg -
Research areas
-
Function
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. -
Pathway
Glycan biosynthesis; glycogen biosynthesis. -
Involvement in disease
Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work. -
Sequence similarities
Belongs to the glycosyltransferase 3 family. - Information by UniProt
-
Alternative names
- Glycogen [starch] synthase
- Glycogen synthase 1
- Glycogen synthase 1 (muscle)
see all -
Database links
- Entrez Gene: 2997 Human
- Omim: 138570 Human
- SwissProt: P13807 Human
- Unigene: 386225 Human
Images
-
Sandwich ELISA - Human Glycogen Synthase 1 Antibody Pair - BSA and Azide free (ab241835)To learn more about the advantages of recombinant antibodies see here.
