Human Ficolin-3 ELISA Kit (ab213779)
Key features and details
- Sensitivity: 20 pg/ml
- Range: 0.78 ng/ml - 50 ng/ml
- Sample type: Cell culture supernatant, Hep Plasma, Serum
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Human
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components Identifier 1 x 96 tests ABC Diluent Buffer Blue Cap 1 x 12ml Adhesive Plate Seal 4 units Antibody Diluent Buffer Green Cap 1 x 12ml Anti-Human Ficolin-3 coated Microplate (12 x 8 wells) 1 unit Avidin-Biotin-Peroxidase Complex (ABC) 1 x 100µl Biotinylated anti- Human Ficolin-3 antibody 1 x 130µl Lyophilized recombinant Human Ficolin-3 standard 2 vials Sample Diluent Buffer Green Cap 1 x 30ml TMB Color Developing Agent Black Cap 1 x 10ml TMB Stop Solution Yellow Cap 1 x 10ml -
Research areas
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Relevance
FCN3 (Ficolin 3) is involved in the serum exerting lectin activity. In human serum, there are two types of ficolins, both of which have lectin activity. FCN3 is a thermolabile beta 2 macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. It can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. -
Cellular localization
Secreted. Note: Found in blood plasma, bronchus, alveolus and bile duct. -
Alternative names
- Collagen/fibrinogen domain containing lectin 3 p35
- Collagen/fibrinogen domain containing protein 3
- FCN 3
see all -
Database links
- Entrez Gene: 8547 Human
- Entrez Gene: 8547 Human
- Omim: 604973 Human
- SwissProt: O75636 Human
Images
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Human Ficolin-3 ELISA Kit (ab213779) Standard Curve.
Human Ficolin-3 ELISA Kit (ab213779) Standard Curve.