HSP70 is a molecular chaperone whose expression is induced upon exposure of the cell or organism to conditions of stress. It prevents protein aggregation and promotes the refolding of proteins that become damaged in response to environmental insults, pathogens, and disease. Its activity is essential for cellular survival and recovery under stress conditions, as well as for the maintenance of normal cellular function under non-stress conditions. HSP70 has been implicated to play a role in a variety of disease and physiological processes such as hyperthermia, hypertension, toxic exposure to chemical agents, hypoxia, ischemia, inflammation, autoimmunity, apoptosis, cancer, organ transplantation, and bacterial and viral infections. HSP70 is also a key regulator of many normal physiological processes including aging, spermatogenesis, menstruation, and physical activity such as exercise. The HSP70 high sensitivity ELISA kit is designed to evaluate and monitor HSP70 in these processes, providing a key research tool to understand the role of HSP70 in physiology and disease.

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