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HBDDE, PKCalpha and PKCgamma inhibitor (ab141573)

Key features and details

  • Selective PKCα and PKCγ inhibitor
  • CAS Number: 154675-18-0
  • Purity: > 97%
  • Soluble in DMSO to 50 mM and in ethanol to 25 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    HBDDE, PKCalpha and PKCgamma inhibitor
  • Description

    Selective PKCα and PKCγ inhibitor
  • Biological description

    PKCα and PKCγ inhibitor (IC50 values are 43 and 50 μM respectively). δ, βI and βII isotypes are not affected. Inducer of apoptosis. Active in vivo.
  • Purity

    > 97%
  • CAS Number

    154675-18-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-(Methoxymethyl)-4-[2,3,4-trihydroxy-6-(methoxymethyl)phenyl]benzene-1,2,3-triol
  • Molecular weight

    338.30
  • Molecular formula

    C16H18O8
  • PubChem identifier

    3568
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 50 mM and in ethanol to 25 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COCC1=CC(=C(C(=C1C2=C(C(=C(C=C2COC)O)O)O)O)O)O
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • Base Excision Repair
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Synthesis
    • DNA Polymerases
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • PKC
    • Neuroscience
    • Neurology process
    • Neurogenesis
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Other factors
    • Stem Cells
    • Hematopoietic Progenitors
    • Intracellular Molecules
    • Epigenetics and Nuclear Signaling
    • Transcription
    • RNA polymerase
    • Epigenetics and Nuclear Signaling
    • Chromatin Binding Proteins
    • DNA / RNA binding
    • Cancer
    • Oncoproteins/suppressors
    • Oncoproteins
    • Transcription factors
    • Stem Cells
    • Hematopoietic Progenitors
    • Hemangioblast
    • Developmental Biology
    • Organogenesis
    • Hematopoietic system development
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Protein Kinase C
    • Inhibitors

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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