GW7647, PPARalpha agonist (ab141124)
Key features and details
- Highly potent, selective PPARα agonist
- CAS Number: 265129-71-3
- Purity: > 99%
- Soluble in DMSO to 25 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GW7647, PPARalpha agonist -
Description
Highly potent, selective PPARα agonist -
Biological description
Highly potent, selective PPARα agonist (EC50 values are 6, 1100 and 6200 nM for PPARα, PPARγ and PPARδ respectively). Pharmacologically active in vivo.
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Purity
> 99% -
CAS Number
265129-71-3 -
Chemical structure
Properties
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Chemical name
2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid -
Molecular weight
502.75 -
Molecular formula
C29H46N2O3S -
PubChem identifier
3392731 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(NC1CCCCC1)N(CCc2ccc(SC(C)(C)C(=O)O)cc2)CCCCC3CCCCC3 -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipases