GSK2578215A, LRRK2 inhibitor (ab254316)
Key features and details
- Potent and selective LRRK2 inhibitor
- CAS Number: 1285515-21-0
- Purity: > 98%
Soluble in DMSO to >75 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GSK2578215A, LRRK2 inhibitor -
Description
Potent and selective LRRK2 inhibitor -
Biological description
Potent and highly selective LRRK2 inhibitor (IC50 = 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2, respectively). Selective for LRRK2 in a panel of 460 kinases. Blood-brain barrier (BBB) permeable.
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Purity
> 98% -
General notes
Protect from air and light.
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CAS Number
1285515-21-0 -
Chemical structure
Properties
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Chemical name
5-(2-Fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
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Molecular weight
399.42 -
Molecular formula
C24H18FN3O2 -
PubChem identifier
68107965 -
Storage instructions
Shipped at 4°C. Store at -20°C. Store In the Dark. -
Solubility overview
Soluble in DMSO to >75 mM
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Handling
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4 -
Source
Synthetic
