GSK 0660, PPARdelta antagonist (ab141428)
Key features and details
- Selective PPARδ antagonist
- CAS Number: 1014691-61-2
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GSK 0660, PPARdelta antagonist -
Description
Selective PPARδ antagonist -
Biological description
Selective PPARδ antagonist (IC50 values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively). Active in vivo. Exhibits inverse agonist effects when administered alone.
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Purity
> 99% -
CAS Number
1014691-61-2 -
Chemical structure
Properties
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Chemical name
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid methyl ester -
Molecular weight
418.48 -
Molecular formula
C19H18N2O5S2 -
PubChem identifier
46233311 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(Nc2ccc(Nc1ccccc1)cc2OC)c3ccsc3C(=O)OC -
Source
Synthetic
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Research areas