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Neuroscience Neurology process Neurodegenerative disease Alzheimer's disease Tangles & Tau

Gemfibrozil, PPARalpha activator (ab142883)

Key features and details

  • PPARα activator
  • CAS Number: 25812-30-0
  • Purity: > 98%
  • Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Gemfibrozil, PPARalpha activator
  • Description

    PPARα activator
  • Biological description

    PPARα activator. Increases the expression of PPAR-β but not PPAR-γ. Shows lipid-lowering and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    25812-30-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
  • Molecular weight

    250.33
  • Molecular formula

    C15H22O3
  • PubChem identifier

    3463
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Alzheimer's disease
    • Tangles & Tau
    • Cardiovascular
    • Blood
    • Serum Proteins
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Nuclear Receptors
    • PPAR
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Metabolism
    • Biochemicals
    • Pharmacology
    • Signaling
    • Lipid signaling
    • Phospholipase & Lipase
    • Activators

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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