Gambogic amide, nerve growth factor (TrKa) receptor agonist (ab141702)
Key features and details
- Potent, selective high affinity nerve growth factor (TrKa) receptor agonist
- CAS Number:
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Gambogic amide, nerve growth factor (TrKa) receptor agonist -
Description
Potent, selective high affinity nerve growth factor (TrKa) receptor agonist -
Biological description
Potent, selective high affinity nerve growth factor (TrKa) receptor agonist (Kd = 75 nM). Antiapoptotic and anticancer agent. Active in vitro and centrally in vivo. -
Purity
> 98% -
Chemical structure
Properties
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Molecular weight
627.80 -
Molecular formula
C38H45NO7 -
PubChem identifier
6710783 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=CCCC1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4=CC5CC6C4(O3)C(C5=O)(OC6(C)C)CC=C(C)C(=O)N)CC=C(C)C)C)C -
Source
Synthetic
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Research areas
