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Fingolimod (FTY720), S1P receptor modulator (ab142065)

Price and availability

53 606 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Potent S1P receptor modulator & novel immunomodulator
  • CAS Number: 162359-56-0
  • Purity: > 98%
  • Soluble in DMSO to 100 mM and in ethanol to 100 mM (with warming)

  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Fingolimod (FTY720), S1P receptor modulator
  • Description

    Potent S1P receptor modulator & novel immunomodulator
  • Biological description

    Potent agonist at four sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5). Novel immunomodulator able to block T-cell egress from lymph nodes. Structural analog of sphingosine. Orally active in vivo. 

  • Purity

    > 98%
  • CAS Number

    162359-56-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride

  • Molecular weight

    343.93
  • Molecular formula

    C19H33NO2.HCl
  • PubChem identifier

    107969
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Soluble in DMSO to 100 mM and in ethanol to 100 mM (with warming)

  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILES

    CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Signal Transduction
    • Cytoskeleton / ECM
    • Cell Adhesion
    • Cell Adhesion Molecules
    • Endothelial
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Cancer
    • Cell Death
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Cardiovascular
    • Angiogenesis
    • Endothelial Cell Markers

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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