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(E,Z)-4-Hydroxytamoxifen (17197F0KYM), estrogen receptor modulator (ab143638)

Key features and details

  • Potent and selective estrogen receptor modulator
  • CAS Number: 68392-35-8
  • Purity: > 97%
  • Soluble in ethanol to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    (E,Z)-4-Hydroxytamoxifen (17197F0KYM), estrogen receptor modulator
  • Description

    Potent and selective estrogen receptor modulator
  • Biological description

    Potent and selective estrogen receptor modulator. Mixture of (Z)-4-Hydroxytamoxifen (ab141943) and (E)-4-Hydroxytamoxifen (ab143637) isomers. Tamoxifen (ab120656) metabolite. Inhibits lipid peroxidation. Shows estrogenic and antiestrogenic effects in vivo. Orally active.
  • Purity

    > 97%
  • CAS Number

    68392-35-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
  • Molecular weight

    387.51
  • Molecular formula

    C26H29NO2
  • PubChem identifier

    63062
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Lipases
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Zinc Finger
    • Signal Transduction
    • Signaling Pathway
    • Lipid Signaling
    • Other
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • Small G Proteins
    • Other
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Progesterone
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • Nuclear Hormone Receptors
    • Estrogen
    • Neuroscience
    • Endocrine system
    • Gonadotrophic axis
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Estrogen
    • Epigenetics and Nuclear Signaling
    • Nuclear Signaling Pathways
    • Nuclear Receptors
    • Progesterone
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
    • Estrogen
    • Cancer
    • Signal transduction
    • Nuclear signaling
    • Nuclear hormone receptors
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    • Diabetes
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    • Obesity
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    • Metabolic disorders

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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