N-Acetyl-S-geranylgeranyl-L-cysteine (AGGC) (ab141618)
Key features and details
- Synthetic substrate of isoprenylated protein methyltransferase
- CAS Number: 139332-94-8
- Purity: > 98%
- Soluble in DMSO to 50 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
N-Acetyl-S-geranylgeranyl-L-cysteine (AGGC) -
Description
Synthetic substrate of isoprenylated protein methyltransferase -
Alternative names
- AGGC
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Biological description
Synthetic substrate of isoprenylated protein methyltransferase (S-adenosylmethionine-dependent methyltransferase). Various pharmacological activities. Inhibits methylation of endogenous isoprenylated proteins. Decreases RhoA carboxyl methylation. Mimics Rab3A and induces insulin release. Inhibits β2-integrin-induced actin polymerization. Acts as an effective inhibitor of fMLP-induced superoxide anion generation. Anti-RSV activity. -
Purity
> 98% -
CAS Number
139332-94-8 -
Chemical structure
Properties
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Chemical name
2-Acetamido-3-(3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenylsulfanyl)propanoic acid -
Molecular weight
435.70 -
Molecular formula
C25H41NO3S -
PubChem identifier
2067 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=CCCC(=CCCC(=CCCC(=CCSCC(C(=O)O)NC(=O)C)C)C)C)C -
Source
Synthetic
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Research areas
