Dynole® 2-24, Dynamin I and II inhibitor (ab141290)
Key features and details
- Novel, potent dynamin I and II inhibitor
- Purity: > 97%
- Supplied in DMSO (50 mM)
- Form / State: Liquid
- Source: Synthetic
Overview
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Product name
Dynole® 2-24, Dynamin I and II inhibitor -
Description
Novel, potent dynamin I and II inhibitor -
Biological description
Novel, potent dynamin I and II inhibitor (IC50 values are 0.56 and 5.4 μM respectively). Shows 4.4-fold selectivity for dynamin I. Highly potent inhibitor of clathrin mediated endocytosis (IC50 = 1.9 μM). Displays low cell toxicity.
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Purity
> 97% -
General notes
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Dynole® is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd. -
Chemical structure
Properties
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Chemical name
N-[[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]methyl]decan-1-amine -
Molecular weight
371.61 -
Molecular formula
C24H41N3 -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Supplied in DMSO (50 mM) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)CCCn2cc(CNCCCCCCCCCC)c1ccccc12 -
Source
Synthetic
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Research areas
