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Neuroscience Neurotransmitter Transporters Glutamate

Dextromethorphan hydrobromide, NMDA receptor antagonist (ab141028)

Price and availability

40 204 ₸

Availability

Order now and get it on Friday March 05, 2021

Key features and details

  • Non-competitive, low affinity NMDA receptor antagonist
  • CAS Number: 125-69-9
  • Purity: > 99%
  • Soluble in water to 50 mM and in ethanol to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Dextromethorphan hydrobromide, NMDA receptor antagonist
  • Description

    Non-competitive, low affinity NMDA receptor antagonist
  • Biological description

    Non-competitive, low affinity NMDA receptor antagonist. Displays antitussive and neuroprotective effects. Active in vivo.

    Also available in simple stock solutions (ab146729) - add 1 ml of water to get an exact, ready-to-use concentration.

  • Purity

    > 99%
  • CAS Number

    125-69-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (9α,13α,14α)-3-Methoxy-17-methylmorphinan hydrobromide
  • Molecular weight

    352.31
  • Molecular formula

    C18H25NO.HBr
  • PubChem identifier

    5462351
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Br.COc3ccc4C[C@@H]1N(C)CC[C@]2(CCCC[C@H]12)c4c3
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Amino Acids
    • Glutamate
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Glutamate Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Ligand-Gated Ion Channels
    • AMPA / Kainate
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cytochromes
    • Signal Transduction
    • Metabolism
    • Drug metabolism
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipases
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Drug metabolism
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Cytochromes
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • NMDA
    • Ion Channel Site
    • Antagonists

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