Desvenlafaxine succinate, SERT and NET inhibitor (ab143602)
Key features and details
- Potent SERT and NET inhibitor. Venlafaxine (ab120715) derivative.
- CAS Number: 386750-22-7
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Desvenlafaxine succinate, SERT and NET inhibitor -
Description
Potent SERT and NET inhibitor. Venlafaxine (ab120715) derivative. -
Biological description
Potent SERT and NET inhibitor (Ki values are 40 and 122 nM for hSERT and hNET respectively). Venlafaxine (ab120715) derivative. Reduces visceral hypersensitivity and delays gastric emptying. Shows antidepressant effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
386750-22-7 -
Chemical structure
Properties
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Chemical name
4-[2-Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol butanedioic acid hydrate -
Molecular weight
399.48 -
Molecular formula
C16H25NO7.C4H6O4.H2O -
PubChem identifier
6918664 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O.C(CC(=O)O)C(=O)O.O -
Source
Synthetic
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Research areas
