Adefovir, Nucleotide analog reverse transcriptase inhibitor (ab143568)
Key features and details
- Nucleotide analog reverse transcriptase inhibitor. Antiviral agent.
- CAS Number: 106941-25-7
- Purity: > 98%
- Soluble in water (with heating). Soluble in NaOH to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Adefovir, Nucleotide analog reverse transcriptase inhibitor -
Description
Nucleotide analog reverse transcriptase inhibitor. Antiviral agent. -
Biological description
Nucleotide analog reverse transcriptase inhibitor (Ki = 100 nM, HBV DNA polymerase). Antiviral agent. cAMP analog. MRP4 substrate. Shows antireplication effects against hepatitis B in vivo. Orally active. -
Purity
> 98% -
CAS Number
106941-25-7 -
Chemical structure
Properties
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Chemical name
2-(6-Aminopurin-9-yl)ethoxymethylphosphonic acid -
Molecular weight
273.19 -
Molecular formula
C8H12N5O4P -
PubChem identifier
60172 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water (with heating). Soluble in NaOH to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=NC2=C(C(=N1)N)N=CN2CCOCP(=O)(O)O -
Source
Synthetic
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Research areas
