[D-Lys3]-GHRP-6 (DLS), Ghrelin receptor (GHS-R1a) and CCR5 antagonist (ab141148)
Key features and details
- Ghrelin receptor (GHS-R1a) and CCR5 antagonist
- CAS Number: 136054-22-3
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
[D-Lys3]-GHRP-6 (DLS), Ghrelin receptor (GHS-R1a) and CCR5 antagonist -
Description
Ghrelin receptor (GHS-R1a) and CCR5 antagonist -
Alternative names
- DLS
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Biological description
Ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM) antagonist. Additionally acts as CCR5 antagonist and blocks HIV-1 propagation. Active in vivo.
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Purity
> 98% -
CAS Number
136054-22-3 -
Chemical structure
Properties
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Molecular weight
930.12 -
Molecular formula
C49H63N13O6 -
Sequence
HWKWFK (Modifications: C-terminal amide; Trp-2 = D-Trp; Lys-3 = D-Lys; Phe-5 = D-Phe) -
PubChem identifier
5311279 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)C[C@H](C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CC4=CNC5=CC=CC=C54)NC(=O)[C@H](CC6=CN=CN6)N -
Source
Synthetic
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Research areas
