Cyclophosphamide, Alkylating agent (ab141240)
Key features and details
- Alkylating agent; chemotherapeutic
- CAS Number: 50-18-0
- Purity: > 99%
- Soluble in water to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cyclophosphamide, Alkylating agent -
Description
Alkylating agent; chemotherapeutic -
Biological description
Alkylating agent; pro-drug capable of inducing DNA single-strand breaks. Efficacious in vitro and in vivo. Chemotherapeutic effects due to inhibition of Bax and Bcl-2 expression when administered with etoposide (ab120227).
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Purity
> 99% -
CAS Number
50-18-0 -
Chemical structure
Properties
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Chemical name
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide -
Molecular weight
261.09 -
Molecular formula
C7H15Cl2N2O2P -
PubChem identifier
2907 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=P1(NCCCO1)N(CCCl)CCCl -
Source
Synthetic
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Research areas
