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Neuroscience Neurotransmitter Transporters Glutamate

CPPG, group II/III metabotropic glutamate receptor antagonist (ab120775)

Price and availability

391 996 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent group II/III metabotropic glutamate receptor antagonist
  • CAS Number: 183364-82-1
  • Purity: > 99%
  • Soluble in 1 eq. NaOH to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CPPG, group II/III metabotropic glutamate receptor antagonist
  • Description

    Potent group II/III metabotropic glutamate receptor antagonist
  • Biological description

    Potent group II/III metabotropic glutamate receptor antagonist. Displays 20-fold selectivity for Group III over Group II. Ki values are 11.5, 17.3 and 4.02 μM for mGlu receptor subtypes mGlu6 mGlu7a and mGlu8a, respectively.

  • Purity

    > 99%
  • CAS Number

    183364-82-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (RS)-α-Cyclopropyl-4-phosphonophenylglycine
  • Molecular weight

    271.21
  • Molecular formula

    C11H14NO5P
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1 eq. NaOH to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Amino Acids
    • Glutamate
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Glutamate Receptors
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR
    • Biochemicals
    • Chemical Type
    • Amino Acid
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • mGlu
    • Group III
    • Antagonists
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • mGlu
    • Group II
    • Antagonists
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • mGlu
    • Group III
    • Antagonists

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