CKI-7 dihydrochloride, Casein kinase 1 inhibitor (ab143760)
Key features and details
- Casein kinase 1 inhibitor. Water soluble analog of CKI-7.
- CAS Number: 1177141-67-1
- Soluble in water to 10 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CKI-7 dihydrochloride, Casein kinase 1 inhibitor -
Description
Casein kinase 1 inhibitor. Water soluble analog of CKI-7. -
Biological description
Casein kinase 1 inhibitor. Water soluble analog of CKI-7 (ab143759). Inhibits SGK, S6K1 and MSK1. Induces retinal cell differentiation. Phosphorylates the inner dynein arm I1 Intermediate Chain. -
CAS Number
1177141-67-1 -
Chemical structure
Properties
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Chemical name
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide dihydrochloride -
Molecular weight
358.67 -
Molecular formula
C11H12ClN3O2S.2HCl -
PubChem identifier
16078955 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=C2C=CN=CC2=C1S(=O)(=O)NCCN)Cl.Cl.Cl -
Source
Synthetic
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Research areas