Cibenzoline, K channel blocker (ab145975)
Key features and details
- ATP-sensitive K channel blocker
- CAS Number: 53267-01-9
- Purity: > 95%
- Soluble in water to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cibenzoline, K channel blocker -
Description
ATP-sensitive K channel blocker -
Alternative names
- 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
- Cifenline
- Cipralan
- Exacor
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Biological description
Class IA antiarrhythmic drug. Blocks ATP-sensitive K channels in heart and pancreatic beta cells. Interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.
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Purity
> 95% -
CAS Number
53267-01-9 -
Chemical structure
Properties
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Chemical name
(±)-2-(2,2-Diphenylcyclopropyl)-2-imidazoline -
Molecular weight
262.35 -
Molecular formula
C18H18N2 -
Storage instructions
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in water to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
