Chloroquine diphosphate, apoptosis and autophagy inhibitor (ab142116)
Key features and details
- Antimalarial; apoptosis and autophagy inhibitor
- CAS Number: 50-63-5
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Chloroquine diphosphate, apoptosis and autophagy inhibitor -
Description
Antimalarial; apoptosis and autophagy inhibitor -
Biological description
Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Binds to Fe(II)-protoporphyrin IX (FP) to form FP-chloroquine complex resulting in cell lysis and parasite cell autodigestion.
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Purity
> 98% -
CAS Number
50-63-5 -
Chemical structure
Properties
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Chemical name
N4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine diphosphate -
Molecular weight
515.87 -
Molecular formula
C18H26ClN3.2H3PO4 -
PubChem identifier
64927 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O -
Source
Synthetic
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Research areas
