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Neuroscience Neurotransmitter Transporters Glutamate

CGP 37849, competitive NMDA antagonist (ab120127)

Price and availability

438 902 ₸

Availability

Order now and get it on Tuesday March 09, 2021

Key features and details

  • Competitive NMDA antagonist
  • CAS Number: 127910-31-0
  • Purity: > 99%
  • Soluble in water to 100 mM (with warming)
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CGP 37849, competitive NMDA antagonist
  • Description

    Competitive NMDA antagonist
  • Biological description

    Competitive NMDA receptor antagonist (Ki = 35 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.

  • Purity

    > 99%
  • CAS Number

    127910-31-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid
  • Molecular weight

    209.14
  • Molecular formula

    C6H12NO5P
  • PubChem identifier

    5950212
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM (with warming)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C/C(=CC(N)C(=O)O)CP(=O)(O)O
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmitter
    • Amino Acids
    • Glutamate
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • GPCR
    • Glutamate Receptors
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Ligand-Gated Ion Channels
    • AMPA / Kainate
    • Neuroscience
    • Neurotransmission
    • Receptors / Channels
    • Ligand-Gated Ion Channels
    • NMDA Receptors
    • Neuroscience
    • Sensory System
    • Somatosensory system
    • Nociception
    • Neuroscience
    • Neurology process
    • Neurodegenerative disease
    • Other
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Amino Acid
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • NMDA
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Addiction
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Alzheimer's Disease
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Depression
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Pain & inflammation
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Parkinson's Disease
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Schizophrenia
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • NMDA
    • Biochemicals
    • Research Area
    • Stroke
    • Glutamate
    • NMDA
    • Glutamate Site
    • Antagonists

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