CFM 2, AMPA receptor antagonist (ab146413)
Key features and details
- Selective, non-competitive AMPA receptor antagonist
- CAS Number: 178616-26-7
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CFM 2, AMPA receptor antagonist -
Description
Selective, non-competitive AMPA receptor antagonist -
Biological description
Selective, non-competitive AMPA receptor antagonist. ERK1/2 pathway inhibitor. Reduces CREB phosphorylation and shows antiproliferative effects. Shows potent, long-acting anticonvulsant effects in vivo.
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Purity
> 98% -
CAS Number
178616-26-7 -
Chemical structure
Properties
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Chemical name
1-(4-Aminophenyl)-3,5-dihydro-7,8-dimethoxy-4H-2,3-benzodiazepin-4-one -
Molecular weight
311.34 -
Molecular formula
C17H17N3O3 -
PubChem identifier
4377504 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C2C(=C1)CC(=O)NN=C2C3=CC=C(C=C3)N)OC -
Source
Synthetic
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Research areas
