Cerivastatin sodium, HMG-CoA reductase inhibitor (ab142853)
Key features and details
- Potent HMG-CoA reductase inhibitor
- CAS Number: 143201-11-0
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cerivastatin sodium, HMG-CoA reductase inhibitor -
Description
Potent HMG-CoA reductase inhibitor -
Biological description
Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active. -
Purity
> 98% -
CAS Number
143201-11-0 -
Chemical structure
Properties
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Chemical name
(E,3R,5S)-7-[4-(4-Fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate sodium -
Molecular weight
481.53 -
Molecular formula
C26H33FNNaO5 -
PubChem identifier
23663992 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C1=C(C(=C(C(=N1)C(C)C)C=CC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)COC.[Na+] -
Source
Synthetic
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Research areas