CDDO methyl ester, Synthetic triterpenoid (ab143795)
Key features and details
- Synthetic triterpenoid.
- CAS Number: 218600-53-4
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
CDDO methyl ester, Synthetic triterpenoid -
Description
Synthetic triterpenoid. -
Alternative names
- 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester
- Bardoxolone Methyl
- CDDO-Me
see all -
Biological description
Synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. Novel therapeutic agent in the treatment of acute myeloid leukemia and pancreatic cancer as well as other forms of cancer.
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CAS Number
218600-53-4 -
Chemical structure
Properties
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Chemical name
2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester -
Molecular weight
505.69 -
Molecular formula
C32H43NO4 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
