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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

CAY10575, IKK-epsilon inhibitor (ab144424)

Key features and details

  • IKK-ε inhibitor
  • CAS Number: 916985-21-2
  • Purity: > 95%
  • Soluble in DMSO to 10 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    CAY10575, IKK-epsilon inhibitor
  • Description

    IKK-ε inhibitor
  • Biological description

    IKK-ε inhibitor (IC50 = 15.8 µM). Benzimidazole (ab143577) derivative.
  • Purity

    > 95%
  • CAS Number

    916985-21-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-(5,6-Dimethoxybenzimidazol-1-yl)-3-[(4-methylsulfonylphenyl)methoxy]thiophene-2-carboxamide
  • Molecular weight

    487.54
  • Molecular formula

    C22H21N3O6S2
  • PubChem identifier

    25190912
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=C(C=C4)S(=O)(=O)C)OC
  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Cell Cycle
    • Kinases/Phosphatases
    • Other
    • Cell Biology
    • Cell Cycle
    • Cell Division
    • Spindle
    • Epigenetics and Nuclear Signaling
    • Cell cycle
    • Kinases/Phosphatases
    • Other
    • Cancer
    • Cell cycle
    • Cell division
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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