Calphostin C, PKC inhibitor (ab142407)
Key features and details
- Potent, selective PKC inhibitor
- CAS Number: 121263-19-2
- Purity: > 95%
Soluble in DMSO
- Form / State: Solid
- Source: Cladosporium cladosporioides
Overview
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Product name
Calphostin C, PKC inhibitor -
Description
Potent, selective PKC inhibitor -
Biological description
Potent protein kinase C inhibitor (IC50 values are 50 and >1000 nM for PKC and PKA respectively). Cell permeable. Active in vivo and in vitro. Inhibits phorbol dibutyrate binding to PKC. -
Purity
> 95% -
CAS Number
121263-19-2 -
Chemical structure
Properties
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Chemical name
1-[3,10-Dihydroxy-12-[2-(4-hydroxyphenoxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-4,9-dioxoperylen-1-yl]propan-2-yl benzoate
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Molecular weight
790.76 -
Molecular formula
C44H38O14 -
PubChem identifier
2533 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CC1=C(C(=C2C(=O)C=C(C3=C4C(=CC(=O)C5=C(C(=C(C(=C45)C1=C32)CC(C)OC(=O)OC6=CC=C(C=C6)O)OC)O)OC)OC)O)OC)OC(=O)C7=CC=CC=C7 -
Source
Cladosporium cladosporioides
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Research areas
