Bryostatin 1, protein kinase C activator (ab142262)
Key features and details
- Potent protein kinase C activator
- CAS Number: 83314-01-6
- Purity: > 98%
- Soluble in DMSO to 25 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Bugula neritina
Overview
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Product name
Bryostatin 1, protein kinase C activator -
Description
Potent protein kinase C activator -
Biological description
Potent protein kinase C activator with high binding affinity (Ki = 1.35 nM). A macrolide lactone. Potently downregulates PKCα, PKCδ and PKCε compared to PMA (ab120297). Range of biological activities. Active in vivo. -
Purity
> 98% -
CAS Number
83314-01-6 -
Chemical structure
Properties
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Molecular weight
905.03 -
Molecular formula
C47H68O17 -
PubChem identifier
5280757 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O -
Source
Bugula neritina
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Research areas