Brucine, Positive allosteric modulator at M1 receptors (ab141042)
Key features and details
- Positive allosteric modulator at M1 receptors
- CAS Number: 357-57-3
- Purity: > 98%
- Soluble in ethanol to 100 mM
- Form / State: Solid
- Source: Strychnos nux-vomica
Overview
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Product name
Brucine, Positive allosteric modulator at M1 receptors -
Description
Positive allosteric modulator at M1 receptors -
Biological description
Positive allosteric modulator at M1 receptors. Proposed to reduce inflammatory mediators including COX-2, PGE2 and thromboxane B2. Able to induce cell apoptosis, with cytotoxic and antiproliferative effects.
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Purity
> 98% -
CAS Number
357-57-3 -
Chemical structure
Properties
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Chemical name
2,3-Dimethoxystrychnidin-10-one -
Molecular weight
394.47 -
Molecular formula
C23H26N2O4 -
PubChem identifier
442021 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc1cc2c(cc1OC)N5C(=O)C[C@@H]4OCC=C3CN7CC[C@]26[C@@H]7C[C@@H]3[C@@H]4[C@H]56 -
Source
Strychnos nux-vomica
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Research areas
