BRL-50481, Selective PDE7 inhibitor (ab141705)
Key features and details
- Selective PDE7 inhibitor
- CAS Number: 433695-36-4
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BRL-50481, Selective PDE7 inhibitor -
Description
Selective PDE7 inhibitor -
Biological description
Selective, competitive PDE7 inhibitor (IC50 values are 0.15 and 12.1 μm for PDE7A and PDE7B respectively). Active in vivo and in vitro. Potentiates the anti-inflammatory effect of PDE4 inhibitor rolipram (ab120031). Cell and blood-brain barrier permeable. -
Purity
> 98% -
CAS Number
433695-36-4 -
Chemical structure
Properties
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Chemical name
3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene -
Molecular weight
244.30 -
Molecular formula
C9H12N2O4S -
PubChem identifier
2921148 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)C -
Source
Synthetic
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Research areas