BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. (ab120520)
Key features and details
- 5-HT1A partial agonist. α adrenoceptor antagonist.
- CAS Number: 21102-95-4
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BMY 7378 dihydrochloride, 5-HT1A partial agonist. alpha adrenoceptor antagonist. -
Description
5-HT1A partial agonist. α adrenoceptor antagonist. -
Biological description
5-HT1A partial agonist (IC50 = 0.8 nM). Potent and selective α1D adrenoceptor antagonist (Ki values are 2, 600 and 800 nM at α1D, α1B and α1A receptors, respectively). Shows antihypertensive activity.
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Purity
> 99% -
CAS Number
21102-95-4 -
Chemical structure
Properties
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Chemical name
8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspirol[4,5]decane-7,9-dione dihydrochloride -
Molecular weight
458.43 -
Molecular formula
C22H31N3O3.2HCl -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas