Betamethasone 21-phosphate sodium salt, glucocorticoid receptor agonist (ab143582)
Key features and details
- Potent glucocorticoid receptor agonist
- CAS Number: 151-73-5
- Purity: > 98%
- Soluble in water to 100 mM and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Betamethasone 21-phosphate sodium salt, glucocorticoid receptor agonist -
Description
Potent glucocorticoid receptor agonist -
Biological description
Potent glucocorticoid receptor agonist (EC50 = 3.1 nM). Betamethasone dipropionate (ab143054) derivative. Shows immunosuppressive, antiallergic, antipruritic and anti-inflammatory effects in vivo. -
Purity
> 98% -
CAS Number
151-73-5 -
Chemical structure
Properties
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Chemical name
[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate disodium salt -
Molecular weight
516.40 -
Molecular formula
C22H28FNa2O8P -
PubChem identifier
65478 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] -
Source
Synthetic
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Research areas
