Bafilomycin C1, Vacuolar-type H+-ATPase inhibitor. (ab144203)
Key features and details
- Vacuolar-type H+-ATPase inhibitor. Na+,K+-ATPase inhibitor. Macrolide antibiotic agent.
- CAS Number: 88979-61-7
- Purity: > 98%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Streptomyces sp.
Overview
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Product name
Bafilomycin C1, Vacuolar-type H+-ATPase inhibitor. -
Description
Vacuolar-type H+-ATPase inhibitor. Na+,K+-ATPase inhibitor. Macrolide antibiotic agent. -
Biological description
Selective vacuolar-type H+-ATPase inhibitor. Na+,K+-ATPase inhibitor. Macrolide antibiotic agent. Shows bacteriostatic effects against Gram-positive bacteria. Shows antifungal effects. -
Purity
> 98% -
CAS Number
88979-61-7 -
Chemical structure
Properties
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Chemical name
(E)-4-[(2R,4R,5S,6R)-2-Hydroxy-2-[(2S,3R,4S)-3-hydroxy-4-[(3S,4Z,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl]-5-methyl-6-propan-2-yloxan-4-yl]oxy-4-oxobut-2-enoic acid -
Molecular weight
720.89 -
Molecular formula
C39H60O12 -
PubChem identifier
6441158 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol and in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@H]1C/C(=C/C=C\[C@@H](C(OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)OC(=O)/C=C/C(=O)O)O)O)OC)/C -
Source
Streptomyces sp.
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Research areas
