SR-9009, REV-ERBalpha/beta agonist (ab146174)
Key features and details
- Potent REV-ERBα/β agonist
- CAS Number: 1379686-30-2
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SR-9009, REV-ERBalpha/beta agonist -
Description
Potent REV-ERBα/β agonist -
Biological description
Potent REV-ERBα/β agonist (IC50 values are 670 and 800 nM for Rev-ErbAα and Rev-ErbAβ-dependent repressor activity respectively). Modulates circadian behavior, shows antiobesogenic and anti-inflammatory effects in vivo. -
CAS Number
1379686-30-2 -
Chemical structure
Properties
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Chemical name
Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate -
Molecular weight
437.94 -
Molecular formula
C20H24ClN3O4S -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)N1CCC(C1)CN(CC2=CC=C(C=C2)Cl)CC3=CC=C(S3)[N+](=O)[O-] -
Source
Synthetic
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Research areas
