Asiatic acid, p38 MAPK activator (ab143120)
Key features and details
- p38 MAPK activator. Apoptotic agent.
- CAS Number: 464-92-6
- Purity: > 99%
- Soluble in DMSO to 200 mM or 98 mg/mL.
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Asiatic acid, p38 MAPK activator -
Description
p38 MAPK activator. Apoptotic agent. -
Biological description
p38 MAPK activator. Apoptotic agent. Induces cell cycle arrest in S-G2/M phase. Upregulates eNOS expression. Inhibts TGF-beta/Smad signaling. Shows antihypertensive and hepatoprotective effects in vivo. Orally active.
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Purity
> 99% -
CAS Number
464-92-6 -
Chemical structure
Properties
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Chemical name
(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-Dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid -
Molecular weight
488.70 -
Molecular formula
C30H48O5 -
PubChem identifier
119034 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 200 mM or 98 mg/mL. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)O -
Source
Synthetic
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Research areas