Apelin 13, Endogenous apelin receptor (APJ) ligand (ab141010)
Key features and details
- Selective endogenous apelin receptor (APJ) ligand
- CAS Number: 217082-58-1
- Purity: > 95%
- Soluble in water to 10 mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Apelin 13, Endogenous apelin receptor (APJ) ligand -
Description
Selective endogenous apelin receptor (APJ) ligand -
Biological description
Selective endogenous apelin receptor (APJ) ligand (EC50 = 0.37 nM). Has a role in cardiovascular regulation and fluid homeostasis. Inhibition of HIV-1 and HIV-2 entry into cells expressing APJ, with potency in the order of apelin 17 (ab141011) >apelin 13.
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Purity
> 95% -
CAS Number
217082-58-1 -
Chemical structure
Properties
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Molecular weight
1550.84 -
Molecular formula
C69H111N23O16S -
Sequence
QRPRLSHKGPMPF -
PubChem identifier
25078060 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N -
Source
Synthetic
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Research areas
