Antibodies, Proteins, Kits and Reagents for Life Science

284 784 ₸ Product size

100 µg 284 784 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-SMYD1 antibody
See all SMYD1 primary antibodies
Description

Rabbit polyclonal to SMYD1
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Human

See all applications and species data
Immunogen

Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human SMYD1.

Read Abcam's proprietary immunogen policy (Peptides available as ab34470, ab34471 and ab34470.)
Positive control
- This antibody gave a positive result in the following lysates: Skeletal Muscle (Human) Tissue Lysate - adult normal tissue. Testis (Human) Tissue Lysate - adult normal tissue.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab32482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Human
All applications	Mouse Chicken

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

Function

Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Sequence similarities

Contains 1 MYND-type zinc finger.
Contains 1 SET domain.
Cellular localization

Cytoplasm. Nucleus.
Target information above from: UniProt accession Q8NB12 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 373960 Chicken
- Entrez Gene: 150572 Human
- Entrez Gene: 12180 Mouse
- Omim: 606846 Human
- SwissProt: Q8NB12 Human
- SwissProt: P97443 Mouse
- Unigene: 516176 Human
- Unigene: 234274 Mouse
- Unigene: 440892 Mouse
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Alternative names
- BOP antibody
- CD8 beta opposite antibody
- CD8b opposite antibody
- Histone lysine N methyltransferase SMYD1 antibody
- KMT3D antibody
- SET and MYND domain containing 1 antibody
- SET and MYND domain-containing protein 1 antibody
- SMYD1 antibody
- SMYD1_HUMAN antibody
- Zinc finger MYND domain containing 18 antibody
- ZMYND18 antibody
- ZMYND22 antibody
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Publishing research using ab32482? Please let us know so that we can cite the reference in this datasheet.

ab32482 has been referenced in 1 publication.

Oka SI et al. Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1. PLoS One 15:e0234913 (2020). PubMed: 32574189