Anti-SARS spike glycoprotein + COVID-19 Spike Protein antibody [CR3022] (ab278112)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Human monoclonal [CR3022] to SARS spike glycoprotein + COVID-19 Spike Protein
- Suitable for: ELISA
- Reacts with: Human coronavirus
Overview
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Product name
Anti-SARS spike glycoprotein + COVID-19 Spike Protein antibody [CR3022] -
Description
Human monoclonal [CR3022] to SARS spike glycoprotein + COVID-19 Spike Protein -
Host species
Human -
Specificity
This antibody binds the amino acids 318-510 in the S1 domain of the SARS-CoV Spike protein as well as SARS-CoV-2 (COVID-19) Spike protein. The antibody also binds to P462L-substituted S318–510 fragments of the SARS spike protein. The binding epitope is only accessible in the "open" conformation of the spike protein (Joyce et al. 2020).
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Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: Human coronavirus -
Immunogen
Other Immunogen Type corresponding to Human coronavirus SARS spike glycoprotein. The original monoclonal antibody was generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV.
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General notes
This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
This antibody does not have a J-chain.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Proclin 300
Constituent: 99.98% PBS -
Carrier free
Yes -
Concentration information loading... -
Purity
Affinity purified -
Purification notes
Affinity Purified using a recombinant lectin column. -
Clonality
Monoclonal -
Clone number
CR3022 -
Isotype
IgA -
Light chain type
kappa -
Research areas