Anti-PLXNA3 antibody (ab41564)
Key features and details
- Rabbit polyclonal to PLXNA3
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-PLXNA3 antibody -
Description
Rabbit polyclonal to PLXNA3 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse
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Immunogen
Synthetic peptide corresponding to Mouse PLXNA3 aa 1100-1200.
(Peptide available asab41563) -
Positive control
- This antibody gave a positive signal in P0 mouse brain and mouse hippocampus tissue lysates
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General notes
Previously labelled as Plexin A3.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab41564 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications HumanApplication Abreviews Notes WB (1) Use a concentration of 1 µg/ml. Detects a band of approximately 207 kDa (predicted molecular weight: 207 kDa).Notes WB
Use a concentration of 1 µg/ml. Detects a band of approximately 207 kDa (predicted molecular weight: 207 kDa).Target
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Relevance
Plexin A3 is a coreceptor for the class 3 secreted semaphorins. This family of semaphorins binds to a complex composed of a neuropilin and a plexin. The plexin type modulates the affinity of the complex for specific semaphorins and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Plexin A3 is a putative receptor involved in the development of neural and epithelial tissues. -
Cellular localization
Membrane; single-pass type I membrane protein. -
Database links
- Entrez Gene: 55558 Human
- Entrez Gene: 18846 Mouse
- Omim: 300022 Human
- SwissProt: P51805 Human
- SwissProt: P70208 Mouse
- Unigene: Hs.632839 Human
- Unigene: Mm.1685 Mouse
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Alternative names
- HSSEXGENE antibody
- Plexin 4 antibody
- Plexin A3 antibody
see all
Images
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Western blot - Anti-PLXNA3 antibody (ab41564)All lanes : Anti-PLXNA3 antibody (ab41564) at 1 µg/ml
Lane 1 : P0 Mouse Brain Mouse Tissue Lysate
Lane 2 : Hippocampus (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 207 kDa
Observed band size: 207 kDa
Additional bands at: 32 kDa, 50 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
Datasheets and documents
References (2)
ab41564 has been referenced in 2 publications.
- Mohan V et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci 39:6233-6250 (2019). PubMed: 31182634
- Demyanenko GP et al. Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling. J Neurosci 34:11274-87 (2014). IHC-FoFr ; Mouse . PubMed: 25143608
Images
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Western blot - Anti-PLXNA3 antibody (ab41564)All lanes : Anti-PLXNA3 antibody (ab41564) at 1 µg/ml
Lane 1 : P0 Mouse Brain Mouse Tissue Lysate
Lane 2 : Hippocampus (Mouse) Tissue Lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Performed under reducing conditions.
Predicted band size: 207 kDa
Observed band size: 207 kDa
Additional bands at: 32 kDa, 50 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes