Antibodies, Proteins, Kits and Reagents for Life Science

284 784 ₸ Product size

100 µg 284 784 ₸ 100 µg 284 784 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-PIG3 antibody
See all PIG3 primary antibodies
Description

Rabbit polyclonal to PIG3
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Human

See all applications and species data
Immunogen

Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human PIG3.

Read Abcam's proprietary immunogen policy (Peptide available as ab68589.)
Positive control
- Recombinant Human PIG3 protein (ab95857) can be used as a positive control in WB. This antibody gave a positive signal in the following lysates: Caco2, A549, WI-38, SW480, TE671, Human Lung Tissue, Human Skeletal Muscle Tissue, Human Colon Tissue

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab64798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Human
All applications	Cow Chimpanzee Rhesus monkey

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).

Function

May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. Has low NADPH-dependent diamine reductase activity (in vitro).
Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Target information above from: UniProt accession Q53FA7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 9540 Human
- Entrez Gene: 704206 Rhesus monkey
- Omim: 605171 Human
- SwissProt: Q53FA7 Human
- Unigene: 50649 Human
Alternative names
- p53 induced gene 3 protein antibody
- p53-induced gene 3 protein antibody
- Putative quinone oxidoreductase antibody
- QORX_HUMAN antibody
- quinone oxidoreductase homolog antibody
- Quinone oxidoreductase PIG3 antibody
- TP53I3 antibody
- Tumor protein p53 inducible protein 3 antibody
- Tumor protein p53-inducible protein 3 antibody
see all

Publishing research using ab64798? Please let us know so that we can cite the reference in this datasheet.

ab64798 has been referenced in 3 publications.

Mungamuri SK et al. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene 0:N/A (2014). PubMed: 25023704
Kracikova M et al. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell Death Differ 20:576-88 (2013). PubMed: 23306555
Mungamuri SK et al. p53-mediated heterochromatin reorganization regulates its cell fate decisions. Nat Struct Mol Biol 19:478-84, S1 (2012). WB . PubMed: 22466965