Anti-gamma Synuclein/SNCG antibody (ab46201)
Key features and details
- Rabbit polyclonal to gamma Synuclein/SNCG
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-gamma Synuclein/SNCG antibody
See all gamma Synuclein/SNCG primary antibodies -
Description
Rabbit polyclonal to gamma Synuclein/SNCG -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide corresponding to Human gamma Synuclein/SNCG aa 100 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin.
(Peptide available asab46713) -
Positive control
- This antibody gave a positive signal in Gamma Synuclein/SNCG recombinant protein.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab46201 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB HumanApplication Abreviews Notes WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa (predicted molecular weight: 13.3 kDa).Use at a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa corresponding to the molecular weight of the full length Gamma Synuclein/SNCG recombinant protein.
Notes WB
Use a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa (predicted molecular weight: 13.3 kDa).Use at a concentration of 0.5 µg/ml. Detects a band of approximately 15 kDa corresponding to the molecular weight of the full length Gamma Synuclein/SNCG recombinant protein.
Target
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Function
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. -
Tissue specificity
Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. -
Sequence similarities
Belongs to the synuclein family. -
Post-translational
modificationsPhosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases. -
Cellular localization
Cytoplasm > perinuclear region. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle. - Information by UniProt
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Database links
- Entrez Gene: 6623 Human
- Omim: 602998 Human
- SwissProt: O76070 Human
- Unigene: 349470 Human
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Alternative names
- BCSG1 antibody
- Breast cancer specific gene 1 protein antibody
- Breast cancer specific protein 1 antibody
see all
Images
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Western blot - Anti-gamma Synuclein/SNCG antibody (ab46201)
Datasheets and documents
References (0)
ab46201 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-gamma Synuclein/SNCG antibody (ab46201)
