Anti-Dystrophin antibody [MANDRA1] (ab7164)
![Anti-Dystrophin antibody [MANDRA1] (ab7164)](https://www.abcam.com/ps/products/7/ab7164/Images/ab7164-292643-anti-dystrophin-antibody-mandra1-immunohistochemistry.jpg "Anti-Dystrophin antibody [MANDRA1] (ab7164)")
Key features and details
- Mouse monoclonal [MANDRA1] to Dystrophin
- Suitable for: IHC-Fr
- Reacts with: Human
- Isotype: IgG1
Overview
-
Product name
Anti-Dystrophin antibody [MANDRA1]
See all Dystrophin primary antibodies -
Description
Mouse monoclonal [MANDRA1] to Dystrophin -
Host species
Mouse -
Tested applications
Suitable for: IHC-Frmore details
Unsuitable for: IHC-P -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein, corresponding to amino acids 3200-3684 of Human Dystrophin.
-
Epitope
128 amino acids at the end of the C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684). -
Positive control
- lympho blastoid cells, cultures of brain astroglial and neuronal cells, liver and Hep G2 cells
-
General notes
The C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx).
This product was changed from ascites to tissue culture supernatant on 17 May 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.097% Sodium azide -
Concentration information loading... -
Purity
Tissue culture supernatant -
Primary antibody notes
The C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx). -
Clonality
Monoclonal -
Clone number
MANDRA1 -
Isotype
IgG1 -
Research areas
Images
-
Immunohistochemistry (Frozen sections) - Anti-Dystrophin antibody [MANDRA1] (ab7164)
ab7164 staining Dystrophin in frozen human tongue tissue sections by Immunohistochemistry (IHC - Fr- Frozen sections). Samples were incubated 1:100 dilution. A Goat Anti-mouse, FITC- conjugate was used as the secondary antibody.
This image was generated using the ascites version of the product.
