Antibodies, Proteins, Kits and Reagents for Life Science

274 732 ₸ Product size

100 µg 274 732 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-5HT1B Receptor antibody
See all 5HT1B Receptor primary antibodies
Description

Rabbit polyclonal to 5HT1B Receptor
Host species

Rabbit
Specificity

This antibody has been sucessfully used on rat tissue in IHC. Since the immunogen only shares 84% homology, customers may get variable results. Please see the abreview for more details.
Tested Applications & Species

Application Species
WB
Human

See all applications and species data
Immunogen

Synthetic peptide corresponding to Human 5HT1B Receptor aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available as ab94829)

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

Batches of this product that have a concentration
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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab85937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Human
All applications	Chimpanzee Gorilla Common marmoset

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).

Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).

Function

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Sequence similarities

Belongs to the G-protein coupled receptor 1 family.
Post-translational
modifications

Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation.
Palmitoylated.
Cellular localization

Cell membrane.
Target information above from: UniProt accession P28222 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 462833 Chimpanzee
- Entrez Gene: 3351 Human
- Omim: 182131 Human
- SwissProt: P60020 Chimpanzee
- SwissProt: Q9N2B7 Gorilla
- SwissProt: P28222 Human
- Unigene: 123016 Human
Alternative names
- 5 HT1DB antibody
- 5 hydroxytryptamine receptor 1B antibody
- 5-HT-1B antibody
- 5-HT-1D-beta antibody
- 5-HT1B antibody
- 5-hydroxytryptamine receptor 1B antibody
- 5HT1B_HUMAN antibody
- Htr1b antibody
- HTR1D2 antibody
- HTR1DB antibody
- S12 antibody
- Serotonin 1D beta receptor antibody
- Serotonin receptor 1B antibody
see all

Publishing research using ab85937? Please let us know so that we can cite the reference in this datasheet.

ab85937 has been referenced in 1 publication.

Kratz A et al. Digital expression profiling of the compartmentalized translatome of Purkinje neurons. Genome Res 24:1396-410 (2014). PubMed: 24904046