Anti-5HT1B Receptor antibody (ab85937)
Key features and details
- Rabbit polyclonal to 5HT1B Receptor
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-5HT1B Receptor antibody
See all 5HT1B Receptor primary antibodies -
Description
Rabbit polyclonal to 5HT1B Receptor -
Host species
Rabbit -
Specificity
This antibody has been sucessfully used on rat tissue in IHC. Since the immunogen only shares 84% homology, customers may get variable results. Please see the abreview for more details. -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide corresponding to Human 5HT1B Receptor aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab94829)
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab85937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB HumanAll applications ChimpanzeeGorillaCommon marmosetApplication Abreviews Notes WB Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).Notes WB
Use a concentration of 1 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).Target
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Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Post-translational
modificationsPhosphorylated. Desensitization of the receptor may be mediated by its phosphorylation.
Palmitoylated. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 462833 Chimpanzee
- Entrez Gene: 3351 Human
- Omim: 182131 Human
- SwissProt: P60020 Chimpanzee
- SwissProt: Q9N2B7 Gorilla
- SwissProt: P28222 Human
- Unigene: 123016 Human
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Alternative names
- 5 HT1DB antibody
- 5 hydroxytryptamine receptor 1B antibody
- 5-HT-1B antibody
see all
Images
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Western blot - Anti-5HT1B Receptor antibody (ab85937)5HT1B Receptor antibody at 1 µg/ml + Human brain tissue lysate - total protein (ab29466) at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 43 kDa
Observed band size: 43 kDa
Exposure time: 20 minutes
Datasheets and documents
References (1)
ab85937 has been referenced in 1 publication.
- Kratz A et al. Digital expression profiling of the compartmentalized translatome of Purkinje neurons. Genome Res 24:1396-410 (2014). PubMed: 24904046
Images
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Western blot - Anti-5HT1B Receptor antibody (ab85937)5HT1B Receptor antibody at 1 µg/ml + Human brain tissue lysate - total protein (ab29466) at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 43 kDa
Observed band size: 43 kDa
Exposure time: 20 minutes
