• Product name

  Annexin V/ANXA5 peptide
  See all Annexin V/ANXA5 proteins and peptides

• Purity

  > 90 % SDS-PAGE.
  
  

• Animal free

  No

• Nature

  Recombinant

• Alternative names

  • Anchorin CII
  • Annexin 5
  • Annexin A5

  • Annexin V
  • Annexin-5
  • Annexin5
  • AnnexinA5
  • AnnexinV
  • ANX 5
  • ANX A5
  • ANX5
  • ANXA5
  • ANXA5_HUMAN
  • Calphobindin I
  • CBP-I
  • Endonexin II
  • ENX 2
  • ENX2
  • Lipocortin V
  • PAP I
  • PAP-I
  • Placental anticoagulant protein 4
  • Placental anticoagulant protein I
  • PLACENTAL PROTEIN 4
  • PP 4
  • Pp4
  • RPRGL3
  • Thromboplastin inhibitor
  • VAC-alpha
  • Vascular anticoagulant-alpha

  see all

• Function

  This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

• Involvement in disease

  Pregnancy loss, recurrent, 3

• Sequence similarities

  Belongs to the annexin family.
  Contains 4 annexin repeats.

• Domain

  The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
  A pair of annexin repeats may form one binding site for calcium and phospholipid.

• Post-translational
  modifications

  S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.

• Target information above from: UniProt accession P08758 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt