Angiotensin III (human, mouse), Endogenous angiotensin receptor peptide (ab141805)
Key features and details
- Endogenous angiotensin receptor peptide
- CAS Number: 13602-53-4
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Angiotensin III (human, mouse), Endogenous angiotensin receptor peptide -
Description
Endogenous angiotensin receptor peptide -
Biological description
Endogenous angiotensin receptor peptide. Displays the same affinity for AT1 and AT2 receptors as Angiotensin II (Asc 183) but also binds to non-AT1/AT2 receptors. Shows antihypertenisve effects and induces aldosterone release in vivo. -
Purity
> 98% -
CAS Number
13602-53-4 -
Chemical structure
Properties
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Molecular weight
931.10 -
Molecular formula
C46H66N12O9 -
Sequence
RVYIHPF -
PubChem identifier
3082042 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N -
Source
Synthetic
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Research areas
Images
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Functional Studies - Angiotensin III (human, mouse), Endogenous angiotensin receptor peptide (ab141805)Angiotensin III induces MAPK activation in IEC-6 cells similar to Angiotensin II.
Cells were incubated in serum depleted medium for 2 h and then stimulated with 0.1 µM and 1 µM Angiotensin III (ab141805) for 10 min or with 0.1 µM and 1 µM Angiotensin II (ab120183) for comparison. Cell proteins were resolved by SDS-PAGE and probed with anti-phospo-ERK1/2.
