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Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Acetylation HAT

Anacardic acid, Histone acetyltransferase (HAT) inhibitor (ab120892)

Price and availability

60 307 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Histone acetyltransferase (HAT) inhibitor
  • CAS Number: 16611-84-0
  • Purity: > 98%
  • Soluble in ethanol to 25 mM and in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Anacardic acid, Histone acetyltransferase (HAT) inhibitor
  • Description

    Histone acetyltransferase (HAT) inhibitor
  • Biological description

    Inhibits HAT activity of p300 and p300/CREB-binding protein-associated factor (pCAF) (IC50 = 8.5 and 5 μM, respectively). Suppresses NF-κB activation, inhibits IκBα phosphorylation and prohibits p65 nuclear translocation
  • Purity

    > 98%
  • CAS Number

    16611-84-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Hydroxy-6-pentadecylbenzoic acid
  • Molecular weight

    348.52
  • Molecular formula

    C22H36O3
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in ethanol to 25 mM and in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCCCc1cccc(O)c1C(=O)O
  • Source

    Synthetic

  • Research areas

    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Acetylation
    • HAT
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Epigenetics
    • Histone Acetyltransferases (HATs)
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Transferase
    • Histone Acetyltransferase (HAT)
    • Biochemicals
    • Research Area
    • Cancer
    • Epigenetics
    • Histone Acetyltransferases (HATs)
    • Biochemicals
    • Research Area
    • Epigenetics
    • Histone Acetyltransferases (HATs)

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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