Amrinone, cAMP phosphodiesterase inhibitor (ab142259)
Key features and details
- Selective cAMP phosphodiesterase inhibitor. Positive inotropic agent.
- CAS Number: 60719-84-8
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Amrinone, cAMP phosphodiesterase inhibitor -
Description
Selective cAMP phosphodiesterase inhibitor. Positive inotropic agent. -
Biological description
Selective cAMP phosphodiesterase inhibitor (IC50 values are 5 and 16 μM for 3A and 3B respectively). Positive inotropic agent. Shows anticonvulsive and vasodilatory effects in vivo. -
Purity
> 98% -
CAS Number
60719-84-8 -
Chemical structure
Properties
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Chemical name
3-Amino-5-pyridin-4-yl-1H-pyridin-2-one -
Molecular weight
187.20 -
Molecular formula
C10H9N3O -
PubChem identifier
3698 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CN=CC=C1C2=CNC(=O)C(=C2)N -
Source
Synthetic
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Research areas
